CMT2A

CMT2A – CMT2A is caused by dominant mutations in Mitofusin 2 (MFN2). The STAR team has developed two good rat models for CMT2A, which are being made available to the research community and represent an important tool to test potential new modulators of mitofusin activity. Stem cell models of CMT2A have also been developed for CMTA-sponsored research in the laboratory of Dr. Robert Baloh, Cedars-Sinai Medical Center.